Science & STEM

Cranial Nerves Labeling Quiz: Identify and Match All 12

Moderate25 Questions13 min

Neuroanatomy students use this cranial nerves labeling quiz to master CN I–XII numbering, names, modality, key foramina, and hallmark deficits used in medical-school gross anatomy practicals and USMLE Step 1 lesion-localization items. It complements cranial nerve quizzes and any cranial nerves quiz/cranial nerve quiz format, including a cranial nerves labeling game, by forcing rapid match-and-label recall.

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1CN I is the olfactory nerve and is purely sensory.

True / False

2Which cranial nerve is responsible for smell?
3CN VIII is responsible for hearing and balance.

True / False

4Which cranial nerve is purely sensory?
5Through which opening does CN XII exit the skull?
6CN VI innervates the lateral rectus muscle to abduct the eye.

True / False

7CN VIII is best described as:
8Taste from the posterior one-third of the tongue travels in CN VII.

True / False

9Which division of CN V passes through the foramen rotundum?
10A patient has horizontal diplopia and cannot abduct the right eye; at rest the right eye is pulled medially. Which cranial nerve is most likely injured?
11Select all that apply. Which cranial nerves carry taste fibers?

Select all that apply

12Which extraocular muscle is the “signature” muscle for CN IV?
13A patient has facial weakness, loss of taste on the anterior 2/3 of the tongue, and reduced lacrimation. Which cranial nerve is most likely affected?
14Both CN VII and CN VIII enter the temporal bone through the:
15Arrange these cranial nerves from CN I to CN VI in correct numerical order by name.

Put in order

1Optic (II)
2Trigeminal (V)
3Trochlear (IV)
4Abducens (VI)
5Olfactory (I)
6Oculomotor (III)
16Select all that apply. Which cranial nerves contribute to the pupillary light reflex?

Select all that apply

17A patient’s tongue deviates to the right on protrusion and shows right-sided atrophy. Which cranial nerve is most likely injured?
18Parasympathetic fibers to the parotid gland travel with which cranial nerve?
19Arrange these foramina by the cranial nerve number that primarily uses them, from lowest-numbered nerve to highest-numbered nerve.

Put in order

1Hypoglossal canal (XII)
2Jugular foramen (IX–XI)
3Foramen ovale (V3)
4Optic canal (II)
20Select all that apply. A lesion affecting CN III can produce which findings?

Select all that apply

21When the right cornea is touched, neither eye blinks. When the left cornea is touched, both eyes blink. Which structure is most likely damaged?
22Select all that apply. Which cranial nerves exit the skull via the jugular foramen?

Select all that apply

23A patient with an internal acoustic meatus mass has progressive hearing loss and episodic vertigo. Which cranial nerve is primarily affected?
24A patient reports vertical diplopia that worsens when walking downstairs. On exam, the affected eye has difficulty depressing when adducted. Which cranial nerve is most likely impaired?
25Arrange the steps of the corneal (blink) reflex from stimulus to response.

Put in order

1Bilateral activation of facial motor nuclei
2Afferent via V1
3Trigeminal sensory nucleus
4Touch cornea
5Efferent via CN VII
6Orbicularis oculi contraction (blink)
Watch Out

High-Yield Cranial Nerve Labeling Traps (I–XII) and How to Fix Them

1) Swapping the extraocular motor nerves (III/IV/VI)

Mistake: treating eye movements as a single blob (“controls the eye”). Fix: label one “signature action” first, then fill in the rest: VI = lateral rectus (abducts), IV = superior oblique (down/in), III = everything else + levator palpebrae + parasympathetic pupil constriction.

2) Guessing modality instead of using it as a sorting step

Mistake: missing easy points on mixed vs pure sensory vs pure motor. Fix: pre-sort choices: sensory only I, II, VIII; motor only III, IV, VI, XI, XII; mixed V, VII, IX, X. Then match functions within the correct bucket.

3) Confusing “face sensation” (V) with “face movement” (VII)

Mistake: labeling facial nerve as the main facial sensory nerve. Fix: write a two-line rule: CN V = facial sensation + muscles of mastication; CN VII = facial expression + taste (anterior 2/3) + lacrimation/salivation.

4) Treating reflexes as trivia

Mistake: missing corneal or gag reflex pairings. Fix: memorize as afferent/efferent pairs: corneal V1 → VII; gag IX → X; pupillary light II → III.

5) Foramina mix-ups (especially V3 vs VII)

Mistake: memorizing a long foramen list with no anchors. Fix: lock “must-know exits”: II optic canal; V2 foramen rotundum; V3 foramen ovale; VII/VIII internal acoustic meatus; IX/X/XI jugular foramen; XII hypoglossal canal; VII exits skull via stylomastoid foramen to face muscles.

Highlights

Cranial Nerves I–XII: Five Labeling Rules That Prevent “Close-but-Wrong” Matches

  1. Start every item by classifying modality, then narrow the answer set. If the prompt is smell/vision/hearing-balance, you’re in I/II/VIII. If it’s tongue movement or shoulder shrug, you’re in XII/XI. This one step prevents random guessing when choices look similar.

  2. Use “signature targets” for the three eye-movement nerves. Anchor first: VI lateral rectus, IV superior oblique, III “the rest” + pupil constriction. On labeling diagrams, place VI at the pons and IV at the dorsal midbrain to reinforce anatomy-function pairing.

  3. Memorize taste + parasympathetic as a map, not a list. Taste: VII anterior 2/3, IX posterior 1/3, X epiglottis. Parasympathetic “big four”: III pupil, VII lacrimal/submandibular/sublingual, IX parotid, X thoracoabdominal viscera.

  4. Pair each nerve with one high-yield foramen to speed skull-base matching. Build a minimal set you can recall under time pressure (e.g., V2 rotundum, V3 ovale, IX/X/XI jugular foramen, XII hypoglossal canal). Then add “bonus exits” only after your accuracy is stable.

  5. Translate lesions into a single observable deficit before picking a nerve. Examples: inability to abduct = VI; tongue deviates toward LMN lesion = XII; loss of facial sensation with weak chewing = V3; hyperacusis + facial weakness suggests VII involvement proximal to stapedius.

Links

Authoritative Cranial Nerve Anatomy & Examination References

FAQ

Cranial Nerves Labeling Quiz FAQ (Foramina, Modalities, Reflexes, Lesion Clues)

What’s the fastest way to stop mixing up CN VII (facial) and CN V (trigeminal) on labeling and matching?

Force a two-step decision: movement vs sensation. Facial expression (smile, close eyes tightly, puff cheeks) is CN VII. Facial skin sensation (V1/V2/V3 dermatomes) and jaw closing strength (masseter/temporalis) is CN V. If the question mentions the corneal reflex, remember V1 is afferent and VII is efferent.

How should I memorize skull exits/foramina without turning it into a giant list?

Build an “anchor set” of exits that cover most exam-style items: II optic canal; V2 foramen rotundum; V3 foramen ovale; VII/VIII internal acoustic meatus; IX/X/XI jugular foramen; XII hypoglossal canal. Once those are automatic, add one detail that distinguishes similar options (e.g., VII exits to facial muscles via the stylomastoid foramen).

Which reflex pairings are most likely to appear in cranial nerve matching questions?

Prioritize three: pupillary light reflex is II → III (afferent optic, efferent oculomotor); corneal reflex is V1 → VII; gag reflex is commonly tested as IX → X. For each, practice converting “absent reflex” into “which limb is broken?” before picking a nerve.

Why do III, IV, and VI questions feel tricky even when I “know” the nerves?

Because many prompts describe the resting eye position after a palsy rather than naming a muscle. Use one rule: identify what movement is lost (abduction = VI; depression in adduction = IV; most other deficits plus ptosis or mydriasis = III). Then confirm with a signature clue: ptosis and pupil involvement strongly point to CN III.

Do I need to know functional components (GSA, SVA, SVE, etc.) for a labeling-focused quiz?

Only to the extent your course uses them. If your items are framed as “special sensory,” “branchial motor,” or “parasympathetic,” translate quickly: smell and taste are special senses (CN I; CN VII/IX/X for taste), hearing/balance is CN VIII, and “branchial motor” typically flags V, VII, IX, X, XI targets in the face/pharynx/larynx/neck.

What laterality rules are high-yield for lesion-style cranial nerve items?

Use two dependable ones: with a CN VI palsy, the affected eye can’t abduct and drifts medially; with a CN XII lower motor neuron lesion, the tongue deviates toward the side of the lesion on protrusion. These are frequent because they convert directly into a single nerve choice without needing extra context.

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Reviewed by
Michael HodgeEdTech Product Lead & Assessment Design SpecialistQuiz Maker
Updated Feb 24, 2026